AR ligand-46
AR ligand-46 is an androgen receptor (AR) ligand that can be used in studies related to PROTAC synthesis, such as serving as a target protein ligand for A031 (HY-148777).
For research use only. We do not sell to patients.
- CAS No.: 2682256-03-5
- Formula: C23H25ClN6O2
- Molecular Weight:452.94
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
AR ligand-46 serves as a target protein ligand for A031 (HY-148777), a PROTAC degrader targeting androgen receptor that induces time-dependent degradation of androgen receptor protein. A031 exerts tumor growth inhibitory effects on zebrafish models transplanted with human prostate cancer cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2682256-03-5
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Molecular Weight 452.94
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Formula C23H25ClN6O2
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SMILES
O=C(N([C@@H]1C2)[C@H](CC1)C[C@@H]2OC3=CC(Cl)=C(C=C3)C#N)C4=CN=C(N5CCNCC5)N=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AR ligand-46 Related Classifications
HY-175937 Related Classifications
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