Bis-Biotin-PEG23
Based on 1 Customer Validation
Bis-Biotin-PEG23 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 97.77%
- CAS No.: 293298-36-9
- Formula: C68H128N6O27S2
- Molecular Weight:1525.90
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Storage:
-20°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 293298-36-9
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Appearance Solid
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Molecular Weight 1525.90
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Formula C68H128N6O27S2
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Color White to off-white
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SMILES
O=C1NC2C(CSC2CCCCC(NCCOCCOCCNC(CCCCC3SCC(N4)C3NC4=O)=O)=O)N1.[22]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Solvent & Solubility
Methanol : 125 mg/mL (81.92 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Methanol | 1 mM | 0.6554 mL | 3.2768 mL | 6.5535 mL | 16.3838 mL |
| 5 mM | 0.1311 mL | 0.6554 mL | 1.3107 mL | 3.2768 mL | |
| 10 mM | 0.0655 mL | 0.3277 mL | 0.6554 mL | 1.6384 mL | |
| 15 mM | 0.0437 mL | 0.2185 mL | 0.4369 mL | 1.0923 mL | |
| 20 mM | 0.0328 mL | 0.1638 mL | 0.3277 mL | 0.8192 mL | |
| 25 mM | 0.0262 mL | 0.1311 mL | 0.2621 mL | 0.6554 mL | |
| 30 mM | 0.0218 mL | 0.1092 mL | 0.2185 mL | 0.5461 mL | |
| 40 mM | 0.0164 mL | 0.0819 mL | 0.1638 mL | 0.4096 mL | |
| 50 mM | 0.0131 mL | 0.0655 mL | 0.1311 mL | 0.3277 mL | |
| 60 mM | 0.0109 mL | 0.0546 mL | 0.1092 mL | 0.2731 mL | |
| 80 mM | 0.0082 mL | 0.0410 mL | 0.0819 mL | 0.2048 mL |
Bis-Biotin-PEG23 Related Classifications
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