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Cat. No.: HY-B1604A

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Chloroprocaine

(Synonyms: 2-Chloroprocaine)

Chloroprocaine (2-Chloroprocaine) is a potent inhibitor of Na,K-ATPase activity with an IC₅₀ of 13 mM. Chloroprocaine blocks peripheral nerve.

For research use only. We do not sell to patients.

CAS No.: 133-16-4
Formula: C₁₃H₁₉ClN₂O₂
Molecular Weight:270.76

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Chloroprocaine Chemical Structure

CAS No.: 133-16-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Chloroprocaine (2-Chloroprocaine) is a potent inhibitor of Na,K-ATPase activity with an IC₅₀ of 13 mM. Chloroprocaine blocks peripheral nerve^[1].

IC₅₀ & Target

IC50: 13 mM (Na,K-ATPase)^[1]

In Vivo

In mice, the intravenous LD₅₀ of Chloroprocaine HCl is 97 mg/kg and the subcutaneous LD₅₀ of Chloroprocaine HCl is 950 mg/kg^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 133-16-4
Molecular Weight 270.76
Formula C₁₃H₁₉ClN₂O₂
SMILES

CCN(CCOC(C1=C(Cl)C=C(N)C=C1)=O)CC
Synonyms

2-Chloroprocaine
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. H Kutchai, et al. Inhibition of the Na,K-ATPase of Canine Renal Medulla by Several Local Anesthetics. Pharmacol Res. 2001 Apr;43(4):399-403. [Content Brief]

[2]. Chloroprocaine HCl Injection.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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