Feruloyl-CoA
Feruloyl-CoA (Feruloyl-coenzyme A) is a cinnamoyl-CoA ester substrate involved in the biosynthesis of lignin and coumarin in plants. Feruloyl-CoA acts as a substrate for cinnamoyl-CoA reductase 1-dependent reduction reaction with NADPH to produce cinnamaldehyde. Feruloyl-CoA is a precursor that generates Scopoletin (HY-N0342) via spontaneous trans/cis isomerization and lactonization of its side chain.
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- CAS No.: 30802-02-9
- Formula: C31H44N7O19P3S
- Molecular Weight:943.70
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Feruloyl-CoA (0.5-5 µM) is efficiently catalyzed and reduced by purified recombinant Arabidopsis enzymes in an NADPH-dependent manner, with a Km value of 0.42 µM, making it one of the most preferred natural substrates for this enzyme[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 30802-02-9
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Molecular Weight 943.70
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Formula C31H44N7O19P3S
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SMILES
NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](OP(O)(O)=O)[C@@H](COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(/C=C/C4=CC(OC)=C(C=C4)O)=O)=O)=O)(O)=O)(O)=O)O3
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Synonyms
Feruloyl-coenzyme A
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Baltas M, et al. Kinetic and inhibition studies of cinnamoyl-CoA reductase 1 from Arabidopsis thaliana. Plant Physiol Biochem. 2005;43(8):746-753. [Content Brief]
[2]. Kai K, et al. Scopoletin is biosynthesized via ortho-hydroxylation of feruloyl CoA by a 2-oxoglutarate-dependent dioxygenase in Arabidopsis thaliana. Plant J. 2008;55(6):989-999. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)