Mark4 - microtubule affinity regulating kinase 4 Gene

Species: Rattus norvegicus

Gene Type: protein coding

Gene ID: 680407

Summary

Predicted to enable protein kinase activity and tubulin binding activity. Predicted to be involved in several processes, including positive regulation of cilium assembly; positive regulation of protein localization to centrosome; and regulation of centrosome cycle. Predicted to be located in several cellular components, including dendrite; microtubule cytoskeleton; and midbody. Predicted to be part of gamma-tubulin complex. Predicted to be active in cytoplasm. Orthologous to human MARK4 (microtubule affinity regulating kinase 4). [provided by Alliance of Genome Resources, Apr 2022]

Mark4 Products (1)

mRNA	Protein	Name
NM_001191071.1	NP_001178000.1	MAP/microtubule affinity-regulating kinase 4

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	22670221	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
MAP/microtubule affinity-regulating kinase 4

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-139604	PCC0208017		99.52%	Unkown
HY-148065	FMF-06-098-1	Inhibitor	98.77%	Unkown
HY-114317	MARK4 inhibitor 1		98.29%	Unkown
HY-148062	RSS0680	Degrader	99.85%	Unkown
HY-154986	MARK4 inhibitor 2	Inhibitor	99.60%	Unkown
HY-154987	MARK4 inhibitor 3		98.23%	Unkown
HY-154988	MARK4 inhibitor 4		99.23%	Unkown
HY-RS08152	MARK4 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS18182	Mark4 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24656	Mark4 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mark4	NCBI	NCBI:57787