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  3. MARK4 inhibitor 3

MAPK4 inhibitor 3 (compound 23b) is an inhibitor of MAPK4 with an IC50 value of 1.01 μM. MAPK4 inhibitor 3 inhibits cancer cells growth. MAPK4 inhibitor 3 can be used for research on cancer and tauopathies.

For research use only. We do not sell to patients.

MARK4 inhibitor 3 Chemical Structure

MARK4 inhibitor 3 Chemical Structure

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Description

MAPK4 inhibitor 3 (compound 23b) is an inhibitor of MAPK4 with an IC50 value of 1.01 μM. MAPK4 inhibitor 3 inhibits cancer cells growth. MAPK4 inhibitor 3 can be used for research on cancer and tauopathies[1].

IC50 & Target

Microtubule affinity-regulating kinase 4 (MARK4)[1] IC50:1.01 μM (Microtubule affinity-regulating kinase 4, MARK4)[1]

In Vitro

MAPK4 inhibitor 3 (1-20 μM, 24 h) inhibits Hela and U87MG growth with EC50 values of 2.52 μM and 4.22 μM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: Hela, U87MG
Concentration: 1-20 μM
Incubation Time: 24 h
Result: Inhibited cell growth with EC50 values of 2.52 μM (Hela), 4.22 μM (U87MG).
Molecular Weight

546.59

Formula

C33H27FN4O3

SMILES

O=C(NC1=CC=C(F)C=C1)[C@@H](NC(CN(C2=C3C=CC=C2)C4=CC=C(C)C=C4C3=O)=O)CC5=CNC6=C5C=CC=C6

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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MARK4 inhibitor 3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
MARK4 inhibitor 3
Cat. No.:
HY-154987
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