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Cat. No.: HY-125324

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Squalestatin 3

Squalestatin 3 is a secondary metabolite, which can be isolated from Phoma. Squalestatin 3 is an inhibitor for squalene synthase with an IC₅₀ of 6 nM.

For research use only. We do not sell to patients.

CAS No.: 142505-92-8
Formula: C₂₅H₃₀O₁₃
Molecular Weight:538.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Squalestatin 3 Chemical Structure

CAS No.: 142505-92-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Squalestatin 3 is a secondary metabolite, which can be isolated from Phoma. Squalestatin 3 is an inhibitor for squalene synthase with an IC₅₀ of 6 nM^[1].

All Endogenous Metabolite Isoforms :

Chemical Information

CAS No. 142505-92-8
Molecular Weight 538.50
Formula C₂₅H₃₀O₁₃
SMILES

OC([C@@]12[C@@](O)([C@H](O[C@@]([C@H](O)[C@H]2O)(CCC([C@@H](OC(C)=O)[C@H](C)CC3=CC=CC=C3)=C)O1)C(O)=O)C(O)=O)=O
Structure Classification
- Others
Initial Source
- Microorganisms
Phoma sp. C2932
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Watson N S, et al. The squalestatins: potent inhibitors of squalene synthase. The role of the tricarboxylic acid moiety[J]. Bioorganic & Medicinal Chemistry Letters, 1993, 3(12): 2541-2546.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Chemical Information
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References

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Squalestatin 3

All Endogenous Metabolite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Squalestatin 3 Related Classifications

HY-125324 Related Classifications