4-Arm-PEG2000-OPSS
4-Arm-PEG2000-OPSS (4-Arm-PEG2000-SPDP) is a four-armed PEG derivative. The core structure of 4-Arm-PEG2000-OPSS consists of four PEG chains, each modified at the end with an o-dithiopyridine (OPSS) group. 4-Arm-PEG2000-OPSS can be used for bioconjugation and drug delivery.
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- CAS No.: 3114600-58-4
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
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Help & FAQs
Activité biologique
The structure of PEG-OPSS comprises two key components that work synergistically:
o-Dithiopyridine (OPSS): Capable of reversibly undergoing disulfide exchange reactions with thiol-containing molecules (-SH), such as cysteine ??residues, thiolized peptides, or proteins, thereby establishing stable disulfide bonds.
PEG chain: Acting as a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing nonspecific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3114600-58-4
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SMILES
O=C(CCSSC1=NC=CC=C1)NCCOCCOCC(COCCOCCNC(CCSSC2=CC=CC=N2)=O)(COCCOCCNC(CCSSC3=NC=CC=C3)=O)COCCOCCNC(CCSSC4=CC=CC=N4)=O.[n].[n].[n].[n]
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Synonyms
4-Arm-PEG2000-SPDP
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Arm-PEG2000-OPSS Related Classifications
HY-W1052890 Related Classifications
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