4-Arm-PEG5000-OPSS
4-Arm-PEG5000-OPSS (4-Arm-PEG5000-SPDP) is a four-armed PEG derivative. The core structure of 4-Arm-PEG5000-OPSS consists of four PEG chains, each modified at the end with an o-dithiopyridine (OPSS) group. 4-Arm-PEG5000-OPSS can be used for bioconjugation and drug delivery.
For research use only. We do not sell to patients.
- CAS No.: 3114600-58-4
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
Biological Activity
The structure of PEG-OPSS comprises two key components that work synergistically:
o-Dithiopyridine (OPSS): Capable of reversibly undergoing disulfide exchange reactions with thiol-containing molecules (-SH), such as cysteine ??residues, thiolized peptides, or proteins, thereby establishing stable disulfide bonds.
PEG chain: Acting as a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing nonspecific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3114600-58-4
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SMILES
O=C(CCSSC1=NC=CC=C1)NCCOCCOCC(COCCOCCNC(CCSSC2=CC=CC=N2)=O)(COCCOCCNC(CCSSC3=NC=CC=C3)=O)COCCOCCNC(CCSSC4=CC=CC=N4)=O.[n].[n].[n].[n]
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Synonyms
4-Arm-PEG5000-SPDP
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Arm-PEG5000-OPSS Related Classifications
HY-W1052890A Related Classifications
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