4-Arm-PEG10000-OPSS
4-Arm-PEG10000-OPSS (4-Arm-PEG10000-SPDP) is a four-armed PEG derivative. The core structure of 4-Arm-PEG10000-OPSS consists of four PEG chains, each modified at the end with an o-dithiopyridine (OPSS) group. 4-Arm-PEG10000-OPSS can be used for bioconjugation and drug delivery.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3114600-58-4
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
The structure of PEG-OPSS comprises two key components that work synergistically:
o-Dithiopyridine (OPSS): Capable of reversibly undergoing disulfide exchange reactions with thiol-containing molecules (-SH), such as cysteine ??residues, thiolized peptides, or proteins, thereby establishing stable disulfide bonds.
PEG chain: Acting as a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing nonspecific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3114600-58-4
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SMILES
O=C(CCSSC1=NC=CC=C1)NCCOCCOCC(COCCOCCNC(CCSSC2=CC=CC=N2)=O)(COCCOCCNC(CCSSC3=NC=CC=C3)=O)COCCOCCNC(CCSSC4=CC=CC=N4)=O.[n].[n].[n].[n]
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別名
4-Arm-PEG10000-SPDP
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)