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Cat. No.: HY-146596

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Axl-IN-5

Axl-IN-5 (compound 1) is a AXL inhibitor with an IC₅₀ of 283 nM. Axl-IN-5 has anticancer effects.

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CAS No.: 2642224-24-4
Formule: C₃₁H₃₅N₅O₂S
Masse moléculaire:541.71

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Axl-IN-5 Chemical Structure

CAS No.: 2642224-24-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Axl-IN-5 (compound 1) is a AXL inhibitor with an IC₅₀ of 283 nM. Axl-IN-5 has anticancer effects^[1].

IC₅₀ & Target

Axl

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Chemical Information

CAS No. 2642224-24-4
Masse moléculaire 541.71
Formule C₃₁H₃₅N₅O₂S
SMILES

CN(S(=O)(C1=C(C=CC=C1)C2=CC=CC3=CN=C(N=C32)NC4=CC5=C(CC[C@@H](CC5)N6CCCC6)C=C4)=O)C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lin-Lin Zhang, et al. Discovery a series of quinazolin derivatives as potent AXL inhibitors. Eur J Med Chem. 2022 Apr 6;237:114316. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

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Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- IC₅₀ & Target
Chemical Information
Pureté et documentation
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Axl-IN-5

Voir tous les produits spécifiques à Isoform TAM Receptor

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Axl-IN-5 Related Classifications

HY-146596 Related Classifications