c-Kit-IN-14
c-Kit-IN-14 (Compound 1) is a c-kit kinase inhibitor. c-Kit-IN-14 inhibits the phosphorylation of wild-type c-kit, with an IC50 of 0.4 nM for pKIT. c-Kit-IN-14 inhibits Exon 11 KIT, with an IC50 of 0.4 nM. c-Kit-IN-14 can be used in the research of mast cell-mediated diseases such as urticaria.
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- CAS No.: 3041025-49-1
- Formule: C26H25ClFN9O3
- Masse moléculaire:565.99
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
IC50: 0.4 nM (pKIT); 0.4 nM (Exon 11 KIT)[1]
Chemical Information
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CAS No. 3041025-49-1
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Masse moléculaire 565.99
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Formule C26H25ClFN9O3
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SMILES
COC[C@H](CN1C=C(C(C)=N1)C2=CC3=C(C=NN3C=C2)C(NC4=C(C=C(C(C5=NN(N=N5)C6CC6)=C4)F)Cl)=O)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)