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Cat. No.: HY-185750

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c-Kit-IN-16

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Based on 1 Customer Validation

C-Kit-IN-16 is a c-kit inhibitor with an IC₅₀ of 25 nM. C-Kit-IN-16 can be used in the research of acute megakaryocytic leukemia.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Pureté: 99.45%
Formule: C₂₂H₂₅N₅O₂
Masse moléculaire:391.47

Stockage:

4°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

c-Kit-IN-16 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

C-Kit-IN-16 is a c-kit inhibitor with an IC₅₀ of 25 nM. C-Kit-IN-16 can be used in the research of acute megakaryocytic leukemia^[1].

In Vitro

C-Kit-IN-16 (Compound 109) (3 days) inhibits the proliferation of M-07e cells, with its IC₅₀ being 12 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Appearance Solid
Masse moléculaire 391.47
Formule C₂₂H₂₅N₅O₂
Color White to off-white
SMILES

CN1C2=CC=C(C=C2NC1=O)C(NCC3=CC=C(N=C3)N(C)C4CC5(C4)CC5)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

4°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Taisuke Takahashi, et al. Kit inhibitors, compounds, pharmaceutical compositions, and methods of use thereof. WO2024029489.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références

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c-Kit-IN-16

MCE Bioactive Compound Library

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

c-Kit-IN-16 Related Classifications

HY-185750 Related Classifications