Cortistatin-8
Based on 1 Customer Validation
Cortistatin-8 (CST-8; PCFWKTCK), a neuropeptide, is a GHS-R1a antagonist by counteracting the response of ghrelin on gastric acid secretion. Cortistatin-8 can modulate GH release from somatotroph cells. Cortistatin-8 is a synthetic CST-analogue devoid of any binding affinity to SST-R but capable to bind the GHS-R1a. Cortistatin-8 can exert antagonistic effects on ghrelin actions either in vitro or in vivo in animals.
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- Pureté: 99.56%
- CAS No.: 485803-62-1
- Formule: C47H68N12O9S2
- Masse moléculaire:1009.25
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Stockage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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GPCR/G Protein Compound Library
HY-L006
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Peptide Library
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Protein-protein Interaction Inhibitor Library
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Membrane Protein-targeted Compound Library
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Membrane Receptor-targeted Compound Library
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Bioactive Compound Library Max
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Peptide Compound Library
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Bioactive Compound Library
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High-Throughput Bioactive Compound Library
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Neuropeptide Library
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Lactylation Compound Library
HY-L249
Activité biologique
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GHSR1a |
Chemical Information
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CAS No. 485803-62-1
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Appearance Solid
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Masse moléculaire 1009.25
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Formule C47H68N12O9S2
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Color White to off-white
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Synonyms
PCFWKTCK
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Sequence
Pro-Cys-Phe-{d-Trp}-Lys-Thr-Cys-Lys-NH2 (disulfide bridge: Cys2-Cys7)
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Sequence Shortening
PCF-{d-Trp}-KTCK-NH2 (disulfide bridge: Cys2-Cys7)
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
DMSO : 16.67 mg/mL (16.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9908 mL | 4.9542 mL | 9.9083 mL | 24.7709 mL |
| 5 mM | 0.1982 mL | 0.9908 mL | 1.9817 mL | 4.9542 mL | |
| 10 mM | 0.0991 mL | 0.4954 mL | 0.9908 mL | 2.4771 mL | |
| 15 mM | 0.0661 mL | 0.3303 mL | 0.6606 mL | 1.6514 mL |
Cortistatin-8 Related Classifications
HY-P1139 Related Classifications
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