Ebselen derivative 1
Ebselen derivative 1 (Compound 19) is a glutathione peroxidase (GPx) mimic with oral activity. Ebselen derivative 1 demonstrates significant protective effects against cisplatin (HY-17394)-induced hair cell (HC) damage both in vitro and in vivo, effectively reducing oxidative stress, apoptosis, and ferroptosis in hair cells. Ebselen derivative 1 can be utilized in the research of cisplatin (HY-17394)-induced hearing loss .
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- CAS No.: 3030492-59-9
- Formule: C13H10N2O2Se
- Masse moléculaire:305.19
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Ebselen derivative 1 (Compound 19) (100 μM) significantly reduces cisplatin (HY-17394) -induced apoptosis and ferroptosis in hair cells and alleviates the surge of oxidative stress triggered by cisplatin throughout the cochlea [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3030492-59-9
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Masse moléculaire 305.19
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Formule C13H10N2O2Se
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SMILES
O=C1C2=C([Se]N1C3=CC=CN=C3)C(OC)=CC=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ebselen derivative 1 Related Classifications
HY-163506 Related Classifications
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