Ferroptosis inducer-5
Ferroptosis inducer-5 (compund 20a) is a ferroptosis inducer.
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- CAS No.: 3043764-74-2
- Formule: C15H14N2O4S
- Masse moléculaire:318.35
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Ferroptosis[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HT-1080 | CC50 |
0.14 μM
Compound: 20a
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Cytotoxicity against human HT-1080 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human HT-1080 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
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[PMID: 39264826] |
| MDA-MB-231 | CC50 |
0.23 μM
Compound: 20a
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Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
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[PMID: 39264826] |
| MEF | CC50 |
0.12 μM
Compound: 20a
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Cytotoxicity against mouse MEF cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against mouse MEF cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
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[PMID: 39264826] |
| NCI-H522 | CC50 |
0.17 μM
Compound: 20a
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Cytotoxicity against human NCI-H522 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human NCI-H522 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
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[PMID: 39264826] |
| NCI-H522 | CC50 |
0.26 μM
Compound: 20a
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Cytotoxicity against human NCI-H522 cells overexpressing GFP-tagged RV assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human NCI-H522 cells overexpressing GFP-tagged RV assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
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[PMID: 39264826] |
| NCI-H522 | CC50 |
1.59 μM
Compound: 20a
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Cytotoxicity against human NCI-H522 cells overexpressing GFP-tagged SLC7A11 assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human NCI-H522 cells overexpressing GFP-tagged SLC7A11 assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
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[PMID: 39264826] |
| U2OS | CC50 |
7.26 μM
Compound: 20a
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Cytotoxicity against human U2OS cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human U2OS cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
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[PMID: 39264826] |
| WI-38 | CC50 |
1.53 μM
Compound: 20a
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Cytotoxicity against human WI-38 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
Cytotoxicity against human WI-38 cells assessed as reduction in cell viability incubated for 3 days by methylene blue staining based spectrophotometric analysis
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[PMID: 39264826] |
Chemical Information
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CAS No. 3043764-74-2
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Masse moléculaire 318.35
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Formule C15H14N2O4S
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SMILES
CC1=C(C2=CSC(C#C)=N2)C/C(C1OC(C)=O)=N\OC(C)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ferroptosis inducer-5 Related Classifications
HY-169146 Related Classifications
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