SP5 - Sp5 transcription factor Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 389058

About SP5

Cytogenetic location: 2q31.1 Genomic coordinates (GRCh38): 2:170,715,337-170,718,078 (from NCBI)

This gene has 2 transcripts (splice variants), 205 orthologues and 22 paralogues. Broad expression in endometrium (RPKM 1.5), prostate (RPKM 0.9) and 16 other tissues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within bone morphogenesis; cellular response to organic cyclic compound; and post-anal tail morphogenesis. Predicted to be located in nucleus. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022]

SP5 Products (1)

mRNA Protein Name
NM_001003845.3 NP_001003845.1 transcription factor Sp5

SP5 Protein Structure

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (312 - 339)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (343 - 365)

  • 0
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  • 300
  • 398 a.a.
Protein Preferred Names Protein Names

transcription factor Sp5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-20897A 5-Bromo-L-tryptophan 99.78% Unkown
HY-RS13608 SP5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-137638 Sp-5,6-DCl-cBIMPS Activator / Unkown
HY-137638A Sp-5,6-DCl-cBIMPS sodium Activator / Unkown
HY-RS12783 SFTPC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W456555 (SP-5-12)-Chloro[[1,1′,1′′,1′′′-tetramethyl 4,4′,4′′,4′′′-(21H,23H-porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN24)tetrakis[benzoato]](2-)]iron / Unkown
HY-W855975 (SP-5-12)-Chloro[[4,4',4'',4'''-(21H,23H-porphine-5,10,15,20-tetrayl-κN21,κN22,κN23,κN24)tetrakis[benzoato]](6-)]Ferrate(3-) / Unkown
HY-W855976 (SP-5-12)-Chloro[5,10,15,20-tetrakis(4-bromophenyl)-21H,23H-porphinato(2-)-N21,N22,N23,N24]iron / Unkown
HY-W855977 (SP-5-12)-Chloro[5,10,15,20-tetrakis(4-bromophenyl)-21H,23H-porphinato(2-)-κN21,κN22,κN23,κN24]manganese / Unkown
HY-RS17444 Sp5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21754 Sftpc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23900 Sp5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-P991311 GSK3178022 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SP5 VGNC VGNC:56148
Mus musculus SP5 MGD MGI:1927715
Macaca mulatta SP5 VGNC VGNC:77921
Canis familiaris SP5 VGNC VGNC:46688
Rattus norvegicus SP5 RGD RGD:1308499
Felis catus SP5 VGNC VGNC:107625
Others SP5 NCBI