Pla2g12b - phospholipase A2, group XIIB Gene

Also Known as Fksg71; hlb218; Pla2g13; 2010002E04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69836

Summary

Predicted to enable calcium ion binding activity and Phospholipase A2 activity. Acts upstream of or within Cholesterol homeostasis; low-density lipoprotein particle remodeling; and triglyceride homeostasis. Predicted to be located in extracellular region. Is expressed in alimentary system; liver; liver lobe; and yolk sac endoderm. Orthologous to human PLA2G12B (Phospholipase A2 group XIIB). [provided by Alliance of Genome Resources, Apr 2022]

Pla2g12b Products (1)

mRNA Protein Name
NM_023530.2 NP_076019.2 group XIIB secretory phospholipase A2-like protein precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Références Source
acts upstream of or within cholesterol homeostasis IMP
IMP: Inferred from mutant phenotype
22912808 MGI
acts upstream of or within low-density lipoprotein particle remodeling IDA
IDA: Inferred from direct assay
27471003 MGI
acts upstream of or within triglyceride homeostasis IMP
IMP: Inferred from mutant phenotype
22912808 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

group XIIB secretory phospholipase A2-like protein

  • GXIIB

  • group XIIB phospholipase A2

  • group XIII secretory phospholipase A2-like protein

  • phospholipase A2, group XIII

  • sPLA2-GXIIB

Recombinant Pla2g12b Proteins

Cat. No. Nom du produit Accession Pureté
HY-P77144 PLA2G12B Protein, Mouse (HEK293, His) Q8VC81 (Q20-L195) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS10618 PLA2G12B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19558 Pla2g12b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26054 Pla2g12b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pla2g12b NCBI NCBI:84647