HBV-IN-45
HBV-IN-45 is a selective and orally active HBV capsid assembly modulator with an IC50 of 0.51 μM for HBcAg in HBC cells. HBV-IN-45 shows potent anti-HBV activities.
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- Formule: C16H16N2O2S
- Masse moléculaire:300.38
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | CC50 |
84.29 μM
Compound: 26f
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Cytotoxicity against human HepG2 cells measured after 3 days by resazurin staining based analysis
Cytotoxicity against human HepG2 cells measured after 3 days by resazurin staining based analysis
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[PMID: 38636128] |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male BALB/c mice injected with replication-competent HBV 1.3 DNA plasmid[1]
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Dosage:100 mg/kg
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Administration:Oral administration; twice daily; for 14 days
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Result:HBV DNA copy numbers were rapidly and markedly reduced in plasma.
Chemical Information
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Masse moléculaire 300.38
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Formule C16H16N2O2S
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SMILES
COC1=CC=C(C=C1)SC2=NC3=CC=CC=C3N2CCO
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HBV-IN-45 Related Classifications
HY-163516 Related Classifications
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