HER2-IN-20
HER2-IN-20 (compound 32) is a potent and selective HER2WT and HER2YVMA inhibitor with IC50 values of 49, 42 nM, respectively. HER2-IN-20 has the potential for the research of non-small cell lung cancer (NSCLC).
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- Formule: C30H27ClFN7O2
- Masse moléculaire:572.03
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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HER2(WT) 49 nM (IC50) |
HER2 YVMA 42 nM (IC50) |
EGFR (WT) 4584 nM (IC50) |
Chemical Information
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Masse moléculaire 572.03
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Formule C30H27ClFN7O2
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SMILES
C=CC(N1[C@@]2([H])C[C@H](N3N=C(C4=CC(F)=C(OC5=CC=C6N(C)C=NC6=C5)C(Cl)=C4)C7=C(C)N=CN=C73)C[C@]1([H])CC2)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)