HsClpP-ligand-1
HsClpP-ligand-1 is an intermediate derived from HsClpP ligands, and also serves as an HsClpP recruitment module for constructing mitochondria-targeted pan-PDK degraders. HsClpP-ligand-1 acts as the HsClpP ligand of the bifunctional degrader Pan-PDK degrader-1 (HY-184943).
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- Formule: C24H23N5O2
- Masse moléculaire:413.47
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
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HsClpP |
HsClpP-ligand-1 (compound 16) is the HsClpP-targeting moiety of the bifunctional degrader Pan-PDK degrader-1 (compound A1) (HY-184943), and forms a stable ternary complex with recombinant human PDK1 and HsClpP[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 413.47
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Formule C24H23N5O2
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SMILES
OC1=C(C=CC=C1)CN2C3=NCCN3C4=C(C2=O)CN(CC4)CC5=CC=CC(C#N)=C5
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HsClpP-ligand-1 Related Classifications
HY-184944 Related Classifications
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