Koninginin D
Koninginin D is a potent antifungal agent that can be isolated from fungi including Trichoderma applanatum. Koninginin D inhibits growth of various fungal species including Gaeumannomyces graminis var. tritici, Bipolaris sorokiniana and so on. Koninginin D can be used for the research of fungal infection.
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- CAS No.: 119903-56-9
- Formule: C16H26O5
- Masse moléculaire:298.37
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Koninginin D inhibits the growth of Listeria monocytogenes, Bacillus subtilis, Pseudomonas aeruginosa, Escherichia coli, Edwardsiella megii, and Vibrio alginolyticus with minimum inhibitory concentrations of 256 μg/mL, 128 μg/mL, and 64 μg/mL, respectively[3].
Koninginin D inhibits the growth of Gaeumannomyces graminis var. tritici, Bipolaris sorokiniana, Pythium middletonii, Fusarium oxysporum, Phytophthora cinnamomi, Rhizoctonia solani at 10 μg/disk and Ceratobasidium cornigerum with an MIC of 64 μg/mL[3].
Koninginin D (50 μM) exhibits significant cytotoxic activity against A549, HeLa, and HepG2 cancer cell lines[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 119903-56-9
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Masse moléculaire 298.37
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Formule C16H26O5
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SMILES
O[C@H]1C2=C([C@@H](CCC2=O)O)O[C@](C1)([H])[C@@H](O)CCCCCC
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Structure Classification
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Initial Source
Trichoderma koningii
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Chen L, et al. Trichodermatides E and F from fungus Trichoderma applanatum. J Asian Nat Prod Res. 2019 Jul;21(7):659-665. [Content Brief]
[2]. Song F, et al. Trichodermaketones A-D and 7-O-methylkoninginin D from the marine fungus Trichoderma koningii. J Nat Prod. 2010;73(5):806-810. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Koninginin D Related Classifications
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