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Cat. No.: HY-114682A

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Lenperone hydrochloride

(Synonyms: AHR 2277)

Lenperone hydrochloride (AHR 2277) is an antipsychotic compound and a dopamine antagonist. Lenperone hydrochloride reduces gastroesophageal sphincter pressure of healthy dogs. Lenperone hydrochloride can be used for neurological disease research.

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CAS No.: 24677-86-9
Formule: C₂₂H₂₄ClF₂NO₂
Masse moléculaire:407.88

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Lenperone hydrochloride Chemical Structure

CAS No.: 24677-86-9

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Activité biologique
- Description
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

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In Vivo

Lenperone hydrochloride (0.16 and 0.44 mg/kg; intramuscular injection; once) decreases mean gastroesophageal sphincter pressure (GESP) of healthy dogs^[1].
Lenperone hydrochloride (0.5, 1.0 and 2.0 mg/kg; subcutaneous injection) shows antipsychotic effects with inducing a dose-dependently cataleptic state and reducing bilateral lesion of the nucleus interstitialis stria terminalis in rats with brain damage^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Healthy adult dogs^[1]
Dosage:

0.16 and 0.44 mg/kg
Administration:

Intramuscular injection; 0.16 and 0.44 mg/kg, once
Result:

Effectively decreased gastroesophageal sphincter pressure (GESP) of dogs.

Chemical Information

CAS No. 24677-86-9
Masse moléculaire 407.88
Formule C₂₂H₂₄ClF₂NO₂
SMILES

O=C(CCCN1CCC(CC1)C(C2=CC=C(C=C2)F)=O)C3=CC=C(C=C3)F.Cl
Synonyms

AHR 2277
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Johnson SE, et al. Effect of lenperone hydrochloride on gastroesophageal sphincter pressure in healthy dogs. Can J Vet Res. 1989 Apr;53(2):248-50. [Content Brief]

[2]. Costall B, Naylor RJ. Mesolimbic involvement with behavioural effects indicating antipsychotic activity. Eur J Pharmacol. 1974 Jun;27(1):46-58. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Pureté et documentation
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Lenperone hydrochloride

Voir tous les produits spécifiques à Isoform Dopamine Receptor

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Lenperone hydrochloride Related Classifications

HY-114682A Related Classifications