24677-86-9
24677-86-9
Chemical Structure
Lenperone hydrochloride
Synonym(s): AHR 2277
- CAS No.: 24677-86-9
- Formula:C22H24ClF2NO2
- Molecular Weight:407.88
IUPAC Name: 4-(4-(4-fluorobenzoyl)piperidin-1-yl)-1-(4-fluorophenyl)butan-1-one hydrochloride
InChIKey: BUPKTBMYUMORNV-UHFFFAOYSA-N
SMILES: O=C(CCCN1CCC(CC1)C(C2=CC=C(C=C2)F)=O)C3=CC=C(C=C3)F.Cl
Biological Activity: Lenperone hydrochloride (AHR 2277) is an antipsychotic compound and a dopamine antagonist. Lenperone hydrochloride reduces gastroesophageal sphincter pressure of healthy dogs. Lenperone hydrochloride can be used for neurological disease research[1][2].
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Lenperone hydrochloride | Lenperone hydrochloride (AHR 2277) is an antipsychotic compound and a dopamine antagonist. Lenperone hydrochloride reduces gastroesophageal sphincter pressure of healthy dogs. Lenperone hydrochloride can be used for neurological disease research. | |||||||||||||||||||||
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References
- [1]. Johnson SE, et al. Effect of lenperone hydrochloride on gastroesophageal sphincter pressure in healthy dogs. Can J Vet Res. 1989 Apr;53(2):248-50. [Content Brief]
- [2]. Costall B, Naylor RJ. Mesolimbic involvement with behavioural effects indicating antipsychotic activity. Eur J Pharmacol. 1974 Jun;27(1):46-58. [Content Brief]
