Lenperone hydrochloride
Lenperone hydrochloride (AHR 2277) is an antipsychotic compound and a dopamine antagonist. Lenperone hydrochloride reduces gastroesophageal sphincter pressure of healthy dogs. Lenperone hydrochloride can be used for neurological disease research.
For research use only. We do not sell to patients.
- CAS No.: 24677-86-9
- Formula: C22H24ClF2NO2
- Molecular Weight:407.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Dopamine Receptor Isoforms
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Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Healthy adult dogs[1]
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Dosage:0.16 and 0.44 mg/kg
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Administration:Intramuscular injection; 0.16 and 0.44 mg/kg, once
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Result:Effectively decreased gastroesophageal sphincter pressure (GESP) of dogs.
Chemical Information
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CAS No. 24677-86-9
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Molecular Weight 407.88
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Formula C22H24ClF2NO2
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SMILES
O=C(CCCN1CCC(CC1)C(C2=CC=C(C=C2)F)=O)C3=CC=C(C=C3)F.Cl
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Synonyms
AHR 2277
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Johnson SE, et al. Effect of lenperone hydrochloride on gastroesophageal sphincter pressure in healthy dogs. Can J Vet Res. 1989 Apr;53(2):248-50. [Content Brief]
[2]. Costall B, Naylor RJ. Mesolimbic involvement with behavioural effects indicating antipsychotic activity. Eur J Pharmacol. 1974 Jun;27(1):46-58. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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