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Cat. No.: HY-W008566S

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Norharmane-¹³C

(Synonyms: Norharman-¹³; β-Carboline-¹³C)

Norharmane-¹³C (Norharman-¹³C) is the ¹³C-labeled Norharmane (HY-W008566). Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC₅₀ values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings.

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Formule: C₁₀¹³CH₈N₂
Masse moléculaire:169.19

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (246 KB)

Norharmane-¹³C Chemical Structure

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Activité biologique
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- Application
Chemical Information
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Activité biologique

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 244-63-3
Masse moléculaire 169.19
Formule C₁₀¹³CH₈N₂
SMILES

C12=CC=CC=C1NC3=[13CH]N=CC=C23
Synonyms

Norharman-¹³; β-Carboline-¹³C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.