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Cat. No.: HY-117481

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NSC-639829

NSC-639829 is a Benzoylphenylurea (BPU) analogue which has antitumor activity. NSC-639829 is promising for research of refractory metastatic cancer.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 134742-19-1
Formule: C₂₁H₂₀BrN₅O₃
Masse moléculaire:470.32

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

NSC-639829 Chemical Structure

CAS No.: 134742-19-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

NSC-639829 is a Benzoylphenylurea (BPU) analogue which has antitumor activity. NSC-639829 is promising for research of refractory metastatic cancer^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
ASPC1	IC₅₀	0.85 μM Compound: 1	Cytotoxicity against human ASPC1 cell line by MTT assay Cytotoxicity against human ASPC1 cell line by MTT assay	[PMID: 16570932]
CWR22R	IC₅₀	1 μM Compound: 1	Cytotoxicity against human CWR22R cell line by MTT assay Cytotoxicity against human CWR22R cell line by MTT assay	[PMID: 16570932]
Hs 766	IC₅₀	1 μM Compound: 1	Cytotoxicity against human HS766 cell line by MTT assay Cytotoxicity against human HS766 cell line by MTT assay	[PMID: 16570932]
HuCCT-1	IC₅₀	1 μM Compound: 11	Inhibitory concentration of compound against growth of human HuCCT-1 cell line Inhibitory concentration of compound against growth of human HuCCT-1 cell line	[PMID: 15081011]
LAPC4	IC₅₀	0.25 μM Compound: 1	Cytotoxicity against human LAPC4 cell line by MTT assay Cytotoxicity against human LAPC4 cell line by MTT assay	[PMID: 16570932]
LNCaP	IC₅₀	0.5 μM Compound: 1	Cytotoxicity against human LnCaP cell line by MTT assay Cytotoxicity against human LnCaP cell line by MTT assay	[PMID: 16570932]
MIA PaCa-2	IC₅₀	0.85 μM Compound: 1	Cytotoxicity against human Miapaca2 cell line by MTT assay Cytotoxicity against human Miapaca2 cell line by MTT assay	[PMID: 16570932]
PANC-1	IC₅₀	0.7 μM Compound: 1	Cytotoxicity against human Panc1 cell line by MTT assay Cytotoxicity against human Panc1 cell line by MTT assay	[PMID: 16570932]
Panc1005	IC₅₀	5 μM Compound: 1	Cytotoxicity against human Panc1005 cell line by MTT assay Cytotoxicity against human Panc1005 cell line by MTT assay	[PMID: 16570932]
Panc203	IC₅₀	0.95 μM Compound: 1	Cytotoxicity against human Panc203 cell line by MTT assay Cytotoxicity against human Panc203 cell line by MTT assay	[PMID: 16570932]
Panc430	IC₅₀	0.8 μM Compound: 1	Cytotoxicity against human Panc430 cell line by MTT assay Cytotoxicity against human Panc430 cell line by MTT assay	[PMID: 16570932]

Chemical Information

CAS No. 134742-19-1
Masse moléculaire 470.32
Formule C₂₁H₂₀BrN₅O₃
SMILES

O=C(NC1=CC=C(C(C)=C1)OC2=NC=C(C=N2)Br)NC(C3=C(N(C)C)C=CC=C3)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Hallur G, et al. Benzoylphenylurea sulfur analogues with potent antitumor activity. J Med Chem. 2006 Apr 6;49(7):2357-60. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

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100 mg

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