Ramifenazone-d7
Ramifenazone-d7 is the deuterium labeled Ramifenazone. Ramifenazone (Isopropylaminoantipyrine) is a pyrazole derivative and acts as a non-steroidal anti-inflammatory agent (NSAID). Ramifenazone has analgesic, antipyretic, anti-inflammatory and antimicrobial activities.
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- CAS No.: 1330180-51-2
- Formule: C14H12D7N3O
- Masse moléculaire:252.36
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1330180-51-2
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Unlabeled Cas 3615-24-5
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Masse moléculaire 252.36
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Formule C14H12D7N3O
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SMILES
O=C1N(N(C)C(C)=C1NC(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])C2=CC=CC=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Bhupender Nehra, et al. Recent advancements in the development of bioactive pyrazoline derivatives. Eur J Med Chem. 2020 Nov 1;205:112666. [Content Brief]
[3]. R Surendra Kumar, et al. Anti-inflammatory and antimicrobial activities of novel pyrazole analogues. Saudi J Biol Sci. 2016 Sep;23(5):614-20. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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