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Cat. No.: HY-169185

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Sigma-2 Radioligand 2

Name: Sigma-2 Radioligand 2
Brand: MedChemExpress
SKU: HY-169185
Price: 430.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Sigma-2 Radioligand 2 (compund 4) exhibits low nanomolar affinity (Ki(σ2)=2.30 nM) and high subtype selectivity (Ki(σ1)/Ki(σ2) > 1500) for the σ2 receptor.

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CAS No.: 2860554-31-8
Formule: C₂₃H₂₈FN₃O₃
Masse moléculaire:413.49

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Sigma-2 Radioligand 2 Chemical Structure

CAS No.: 2860554-31-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
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Chemical Information
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Activité biologique

Description

Sigma-2 Radioligand 2 (compund 4) exhibits low nanomolar affinity (Ki(σ2)=2.30 nM) and high subtype selectivity (Ki(σ1)/Ki(σ2) > 1500) for the σ2 receptor^[1].

IC₅₀ & Target

σ2 receptor^[1]

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Chemical Information

CAS No. 2860554-31-8
Masse moléculaire 413.49
Formule C₂₃H₂₈FN₃O₃
SMILES

O=C1N(C2=CC=CC=C2N1CCCCN3CC4=C(C3)C=C(OC)C(OC)=C4)CCF
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Wang J, et al. Novel 18F-labeled benzimidazolone-based radioligands as highly selective sigma-2 receptor probes for tumor imaging[J]. Journal of Medicinal Chemistry, 2024, 67(19): 17392-17406.

Calculators

Calculateur de molarité

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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Sigma-2 Radioligand 2

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