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Cat. No.: HY-176181

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Thalidomide-4-PEG4-OTs

Thalidomide-4-OH-PEG4-OTs is an E3 ligase ligand-linker conjugate that incorporates the Thalidomide (HY-14658) based CRBN ligand (HY-103596) and 4-unit PEG linker (HY-176182). Thalidomide-4-OH-PEG4-OTs can be used for synthesis of PROTAC STING degrader-4 (HY-176180).

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CAS No.: 3023389-80-9
Formule: C₂₈H₃₂N₂O₁₁S
Masse moléculaire:604.63

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

Thalidomide-4-PEG4-OTs Chemical Structure

CAS No.: 3023389-80-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

Voir tous les produits spécifiques à Isoform E3 Ligase Ligand-Linker Conjugates :

Chemical Information

CAS No. 3023389-80-9
Masse moléculaire 604.63
Formule C₂₈H₃₂N₂O₁₁S
SMILES

O=C(N1C2CCC(NC2=O)=O)C3=C(OCCOCCOCCOCCOS(C4=CC=C(C=C4)C)(=O)=O)C=CC=C3C1=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. An Y, et al. Discovery of indole derivatives as STING degraders. Eur J Med Chem. 2025 May 12; 294:117747. [Content Brief]

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Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Thalidomide-4-PEG4-OTs

Voir tous les produits spécifiques à Isoform E3 Ligase Ligand-Linker Conjugates

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Thalidomide-4-PEG4-OTs Related Classifications

HY-176181 Related Classifications