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Cat. No.: HY-145499

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XTT sodium hydrate

4 Cited Publications

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Based on 4 publication(s) in Google Scholar

XTT is a cell-impermeable, negatively charged tetrazolium dye that produces a water-soluble formazan when reduced at the cell surface by cellular-derived NADH and an electron mediator. It is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis.

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CAS No.: 413585-64-5
Formule: C₂₂H₁₈N₇NaO₁₄S₂

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

XTT sodium hydrate Chemical Structure

CAS No.: 413585-64-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

Chemical Information

CAS No. 413585-64-5
Formule C₂₂H₁₈N₇NaO₁₄S₂
SMILES

O=C(C1=NN([N+](C2=C(OC)C=C([N+]([O-])=O)C(S(=O)([O-])=O)=C2)=N1)C3=C(OC)C=C([N+]([O-])=O)C(S(=O)(O[Na])=O)=C3)NC4=CC=CC=C4.O.[x]
Livraison

Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (4)

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J Nanobiotechnology

A novel tetrahedral framework nucleic acid-based antibiotic delivery system: overcoming biofilm barriers to combat chronic infections. [Abstract]

2025 Jul 1;23(1):465. PMID: 40597263

XTT sodium hydrate purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2025 Jul 1;23(1):465. [Abstract]

Biofilm eradication rates of PMB@Td and PMB@Lipo at different concentrations was determined by XTT sodium (100 µL; 1 mg/mL) assays.
J Med Chem

Activity and Safety Optimization of Mesoricin: A Dual-Domain Antifungal Peptide from Mesorhizobium sp. [Abstract]

2025 Apr 8. PMID: 40198836

XTT sodium hydrate purchased from MedChemExpress. Usage Cited in: J Med Chem. 2025 Apr 8. [Abstract]

XTT sodium (150 μL; 0.5 mg/mL; 3 h; 37 ℃) was used to assess biofilm inhibition and eradication of C. neoformans H99 by mesoricin1 and mesoricin4 at different concentrations.
Molecules

Chemical Characterization, Evaluation of Antimicrobial Potential, and Cytotoxic Activity of Thuja occidentalis L. and Myrtus communis L. Essential Oils for Topical Applications. [Abstract]

2026 Apr 7;31(7):1225. PMID: 41976265
Curr Microbiol

Berberine Hydrochloride Enhances the Fluconazole Susceptibility of Candida albicans through Multiple Targets. [Abstract]

2026 Mar 27;83(5):262. PMID: 41896451

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Sutherland, et al. The tetrazolium dyes MTS and XTT provide new quantitative assays for superoxide and superoxide dismutase. Free Radic. Res. 27(3), 283-289 (1997).

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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XTT sodium hydrate

4 Cited Publications

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XTT sodium hydrate purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2025 Jul 1;23(1):465. [Abstract]

Customer Validation
Biofilm eradication rates of PMB@Td and PMB@Lipo at different concentrations was determined by XTT sodium (100 µL; 1 mg/mL) assays.
1/16

XTT sodium hydrate purchased from MedChemExpress. Usage Cited in: J Med Chem. 2025 Apr 8. [Abstract]

Customer Validation
XTT sodium (150 μL; 0.5 mg/mL; 3 h; 37 ℃) was used to assess biofilm inhibition and eradication of C. neoformans H99 by mesoricin1 and mesoricin4 at different concentrations.

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XTT sodium hydrate

Publications Citing Use of MedChemExpress (MCE) XTT sodium hydrate

Activité biologique

Chemical Information

Publications (4)

Pureté et documentation

Références

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XTT sodium hydrate Related Classifications

HY-145499 Related Classifications