1000998-59-3
1000998-59-3
Chemical Structure
BMS-687453
- CAS No.: 1000998-59-3
- Formula:C22H21ClN2O6
- Molecular Weight:444.86
IUPAC Name: N-(3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)-N-(methoxycarbonyl)glycine
InChIKey: UJIBXDMNCMEJAY-UHFFFAOYSA-N
SMILES: ClC(C=C1)=CC=C1C2=NC(COC3=CC=CC(CN(C(OC)=O)CC(O)=O)=C3)=C(C)O2
Biological Activity: BMS-687453 is a potent and selective PPARα agonist, with an EC50 and IC50 of 10 nM and 260 nM for human PPARα and 4100 nM and >15000 nM for PPARγ in PPAR-GAL4 transactivation assays.
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BMS-687453 | 99.31% | BMS-687453 is a potent and selective PPARα agonist, with an EC50 and IC50 of 10 nM and 260 nM for human PPARα and 4100 nM and >15000 nM for PPARγ in PPAR-GAL4 transactivation assays. | ||||||||||||||||||||
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BMS-687453 (Standard) | BMS-687453 (Standard) is the analytical standard of BMS-687453 (HY-10678). This product is intended for research and analytical applications. BMS-687453 is a potent and selective PPARα agonist, with an EC50 and IC50 of 10 nM and 260 nM for human PPARα and 4100 nM and >15000 nM for PPARγ in PPAR-GAL4 transactivation assays. | |||||||||||||||||||||
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Keywords
