76541-72-5
76541-72-5
Chemical Structure
Mifobate
Synonym(s): SR-202
- CAS No.: 76541-72-5
- Formula:C11H17ClO7P2
- Molecular Weight:358.65
IUPAC Name: (4-chlorophenyl)(dimethoxyphosphoryl)methyl dimethyl phosphate
InChIKey: VQHUQHAPWMNBLP-UHFFFAOYSA-N
SMILES: O=P(OC)(OC)OC(C1=CC=C(Cl)C=C1)P(OC)(OC)=O
Biological Activity: Mifobate (SR-202) is a potent and specific PPARγ antagonist. Mifobate (SR-202) selectively inhibits Thiazolidinedione (TZD)-induced PPARγ transcriptional activity (IC50=140 μM). Mifobate (SR-202) does not affect basal or ligand-stimulated transcriptional activity of PPARα, PPARβ, or the farnesoid X receptor (FXR). Mifobate (SR-202) shows antiobesity and antidiabetic effects[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Mifobate | 99.85% | Mifobate (SR-202) is a potent and specific PPARγ antagonist. Mifobate (SR-202) selectively inhibits Thiazolidinedione (TZD)-induced PPARγ transcriptional activity (IC50=140 μM). Mifobate (SR-202) does not affect basal or ligand-stimulated transcriptional activity of PPARα, PPARβ, or the farnesoid X receptor (FXR). Mifobate (SR-202) shows antiobesity and antidiabetic effects. | ||||||||||||||||||||
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Mifobate (Standard) | ≥98% | Mifobate (Standard) is the analytical standard of Mifobate. This product is intended for research and analytical applications. Mifobate (SR-202) is a potent and specific PPARγ antagonist. Mifobate (SR-202) selectively inhibits Thiazolidinedione (TZD)-induced PPARγ transcriptional activity (IC50=140 μM). Mifobate (SR-202) does not affect basal or ligand-stimulated transcriptional activity of PPARα, PPARβ, or the farnesoid X receptor (FXR). Mifobate (SR-202) shows antiobesity and antidiabetic effects. | ||||||||||||||||||||
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HNMPA | 99.89% | HNMPA is a membrane impermeable insulin receptor tyrosine kinase inhibitor. HNMPA inhibits serine and tyrosine autophosphorylation by the human insulin receptor. HNMPA has no effect on protein kinase C or cyclic AMP-dependent protein kinase activities | ||||||||||||||||||||
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PDM11 | 99.93% | PDM11 is a derivative of antioxidant resveratrol. PDM11 do not exhibit any significant protective effect against oxidation of linoleate micelles initiated by radiolysis-generated hydroxyl radicals. PDM11 is inactive in resveratrol activity assays. | ||||||||||||||||||||
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Tetrachlorvinphos (Standard) | ≥98% | Tetrachlorvinphos (Standard) is the analytical standard of Tetrachlorvinphos. This product is intended for research and analytical applications. Tetrachlorvinphos is an organophosphorus pesticide that has the activity of inhibiting cholinesterase. Tetrachlorvinphos is used as a pesticide, mainly for the control of pests. Tetrachlorvinphos has low toxicity to mammals. | ||||||||||||||||||||
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(Z)-Tetrachlorvinphos-d6 | (Z)-Tetrachlorvinphos-d6 is the deuterium labeled Tetrachlorvinphos (HY-126199). Tetrachlorvinphos is an organophosphorus pesticide that has the activity of inhibiting cholinesterase. Tetrachlorvinphos is used as a pesticide, mainly for the control of pests. Tetrachlorvinphos has low toxicity to mammals. | |||||||||||||||||||||
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((Benzylazanediyl)bis(methylene))bis(phosphonic acid) | ((Benzylazanediyl)bis(methylene))bis(phosphonic acid) ([Benzyl(phosphonomethyl)amino]methylphosphonic acid) is a metal-organic framework (MOF). | |||||||||||||||||||||
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(1,2-Phenylenebis(methylene))bis(phosphonic acid) | (1,2-Phenylenebis(methylene))bis(phosphonic acid) (o-Xylylenediphosphonic Acid) is a metal-organic framework (MOF). | |||||||||||||||||||||
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((2,4,6-Trimethylbenzene-1,3,5-triyl)tris(methylene))tris(phosphonic acid) | ((2,4,6-Trimethylbenzene-1,3,5-triyl)tris(methylene))tris(phosphonic acid) is a metal-organic framework (MOF). | |||||||||||||||||||||
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(Benzene-1,3,5-triyltris(methylene))tris(phosphonic acid) | (Benzene-1,3,5-triyltris(methylene))tris(phosphonic acid) is a metal-organic framework (MOF). | |||||||||||||||||||||
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5-(Phosphonomethyl)isophthalic acid | 5-(Phosphonomethyl)isophthalic acid is a metal-organic framework (MOF). | |||||||||||||||||||||
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Methyl-Bn-PEG3-OH | Methyl-Bn-PEG3-OH is a PROTAC linker that can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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