874101-00-5
874101-00-5
Chemical Structure
RO4987655
Synonym(s): CH4987655
- CAS No.: 874101-00-5
- Formula:C20H19F3IN3O5
- Molecular Weight:565.28
IUPAC Name: 3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)-N-(2-hydroxyethoxy)-5-((3-oxo-1,2-oxazinan-2-yl)methyl)benzamide
InChIKey: FIMYFEGKMOCQKT-UHFFFAOYSA-N
SMILES: FC(C(F)=C(NC1=CC=C(I)C=C1F)C(C(NOCCO)=O)=C2)=C2CN3C(CCCO3)=O
Biological Activity: RO4987655 is an orally active and highly selective MEK inhibitor with an IC50 of 5.2 nM for inhibition of MEK1/MEK2.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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RO4987655 | 99.01% | RO4987655 is an orally active and highly selective MEK inhibitor with an IC50 of 5.2 nM for inhibition of MEK1/MEK2. | ||||||||||||||||||||
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RO4987655 (Standard) | ≥98% | RO4987655 (Standard) is the analytical standard of RO4987655. This product is intended for research and analytical applications. RO4987655 is an orally active and highly selective MEK inhibitor with an IC50 of 5.2 nM for inhibition of MEK1/MEK2. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.62
HY-12062PD318088 -
Similarity Score 0.61
HY-131295PD0325901-O-C2-dioxolane -
Similarity Score 0.60
HY-107620PD 198306 -
Similarity Score 0.59
HY-10254Mirdametinib -
Similarity Score 0.59
HY-185446KZ-02 -
Similarity Score 0.59
HY-132844Tunlametinib -
Similarity Score 0.56
HY-10174PD184161 -
Similarity Score 0.55
HY-111368EBI-1051 -
Similarity Score 0.55
HY-12058AZD8330 -
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