Biotin-PEG7-amine
Based on 1 Customer Validation
Biotin-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- Reinheit: 98.0%
- CAS. Nr.: 1334172-76-7
- Formel: C26H50N4O9S
- Molecular Weight:594.76
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Speicherung:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1334172-76-7
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Appearance Solid-Liquid Mixture
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Molecular Weight 594.76
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Formel C26H50N4O9S
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Color White to off-white
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SMILES
O=C(NCCOCCOCCOCCOCCOCCOCCOCCN)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
H2O : 83.33 mg/mL (140.11 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (265 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.6814 mL | 8.4068 mL | 16.8135 mL | 42.0338 mL |
| 5 mM | 0.3363 mL | 1.6814 mL | 3.3627 mL | 8.4068 mL | |
| 10 mM | 0.1681 mL | 0.8407 mL | 1.6814 mL | 4.2034 mL | |
| 15 mM | 0.1121 mL | 0.5605 mL | 1.1209 mL | 2.8023 mL | |
| 20 mM | 0.0841 mL | 0.4203 mL | 0.8407 mL | 2.1017 mL | |
| 25 mM | 0.0673 mL | 0.3363 mL | 0.6725 mL | 1.6814 mL | |
| 30 mM | 0.0560 mL | 0.2802 mL | 0.5605 mL | 1.4011 mL | |
| 40 mM | 0.0420 mL | 0.2102 mL | 0.4203 mL | 1.0508 mL | |
| 50 mM | 0.0336 mL | 0.1681 mL | 0.3363 mL | 0.8407 mL | |
| 60 mM | 0.0280 mL | 0.1401 mL | 0.2802 mL | 0.7006 mL | |
| 80 mM | 0.0210 mL | 0.1051 mL | 0.2102 mL | 0.5254 mL | |
| 100 mM | 0.0168 mL | 0.0841 mL | 0.1681 mL | 0.4203 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.