CSBP ligand 1
CSBP ligand 1 (Compound 36) is a ligand of CSBP, with an IC50 of 0.08 μM for CSBP binding. CSBP ligand 1 can inhibit the production of TNF in mice treated with LPS (HY-D1056). CSBP ligand 1 has no significant inhibitory activity against PGHS-1 (IC50: 16 μM) and 5-LO (IC50: 60 μM). CSBP ligand 1 can be used in the research of inflammation-related diseases.
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- CAS. Nr.: 165806-32-6
- Formel: C17H14FN3
- Molecular Weight:279.31
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RBL-1 | IC50 |
60 μM
Compound: 36
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Inhibitory concentration against 5-lipoxygenase in rat RBL-1 cells
Inhibitory concentration against 5-lipoxygenase in rat RBL-1 cells
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[PMID: 8831759] |
Chemical Information
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CAS. Nr. 165806-32-6
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Molecular Weight 279.31
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Formel C17H14FN3
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SMILES
FC1=CC=C(C2=C(C3=CC=NC=C3)N(C4CC4)C=N2)C=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CSBP ligand 1 Related Classifications
HY-178214 Related Classifications
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