165806-32-6
165806-32-6
Chemical Structure
CSBP ligand 1
- CAS No.: 165806-32-6
- Formula:C17H14FN3
- Molecular Weight:279.31
InChIKey: VXSHGJJXHHEQII-UHFFFAOYSA-N
SMILES: FC1=CC=C(C2=C(C3=CC=NC=C3)N(C4CC4)C=N2)C=C1
Biological Activity: CSBP ligand 1 (Compound 36) is a ligand of CSBP, with an IC50 of 0.08 μM for CSBP binding. CSBP ligand 1 can inhibit the production of TNF in mice treated with LPS (HY-D1056). CSBP ligand 1 has no significant inhibitory activity against PGHS-1 (IC50: 16 μM) and 5-LO (IC50: 60 μM). CSBP ligand 1 can be used in the research of inflammation-related diseases[1].
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CSBP ligand 1 | CSBP ligand 1 (Compound 36) is a ligand of CSBP, with an IC50 of 0.08 μM for CSBP binding. CSBP ligand 1 can inhibit the production of TNF in mice treated with LPS (HY-D1056). CSBP ligand 1 has no significant inhibitory activity against PGHS-1 (IC50: 16 μM) and 5-LO (IC50: 60 μM). CSBP ligand 1 can be used in the research of inflammation-related diseases. | |||||||||||||||||||||
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References
Keywords
