EBOV/MARV-IN-3
EBOV/MARV-IN-3 (compound 32) is a potent EBOV and MARV inhibitor with IC50 values of 0.5, 1.2 µM, respectively. EBOV/MARV-IN-3 binds to the hydrophobic pocket close to EBOV Y517. EBOV/MARV-IN-3 shows antiviral activity.
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- CAS. Nr.: 2687245-05-0
- Formel: C27H29F3N2O6
- Molecular Weight:534.52
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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EBOV |
MARV |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | CC50 |
68.2 μM
Compound: 32
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Cytotoxicity against human A549 cells assessed as reduction in cell viability by Celltiter-Glo assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability by Celltiter-Glo assay
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[PMID: 32707357] |
Chemical Information
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CAS. Nr. 2687245-05-0
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Molecular Weight 534.52
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Formel C27H29F3N2O6
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SMILES
CC1=C(C(OC2=CC(OCC(CN3CCC(CC3)C(N)=O)O)=CC=C21)=O)CC4=CC=C(C=C4)OC(F)(F)F
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
EBOV/MARV-IN-3 Related Classifications
HY-146814 Related Classifications
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