Adcy10 - adenylate cyclase 10 Gene

Also Known as Sac

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 59320

Summary

Enables ATPase binding activity; Adenylate Cyclase activity; and manganese ion binding activity. Involved in cAMP biosynthetic process and positive regulation of apoptotic process. Located in several cellular components, including basal part of cell; growth cone; and neuronal cell body. Orthologous to human ADCY10 (Adenylate Cyclase 10). [provided by Alliance of Genome Resources, Apr 2022]

Adcy10 Products (1)

mRNA Protein Name
NM_021684.1 NP_067716.1 adenylate cyclase type 10

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables ATPase binding IPI
IPI: Inferred from physical interaction
17959750 RGD
enables adenylate cyclase activity IDA
IDA: Inferred from direct assay
7225326 RGD
enables manganese ion binding IDA
IDA: Inferred from direct assay
7225326 RGD
Biological Process GO Annotation Evidence Verweise Source
involved in cAMP biosynthetic process IDA
IDA: Inferred from direct assay
7225326 RGD
involved in cAMP biosynthetic process IMP
IMP: Inferred from mutant phenotype
16627466 RGD
involved in glucose catabolic process IMP
IMP: Inferred from mutant phenotype
22998876 RGD
involved in mitochondrial ATP transmembrane transport IMP
IMP: Inferred from mutant phenotype
32664470 RGD
involved in negative regulation of cardiac muscle cell contraction IMP
IMP: Inferred from mutant phenotype
31754830 RGD
involved in negative regulation of mitochondrial membrane potential IMP
IMP: Inferred from mutant phenotype
28386847 RGD
involved in negative regulation of reactive oxygen species biosynthetic process IMP
IMP: Inferred from mutant phenotype
32664470 RGD
involved in neuron projection extension IMP
IMP: Inferred from mutant phenotype
25009261 RGD
involved in neuron projection maintenance IMP
IMP: Inferred from mutant phenotype
22649251 RGD
involved in neuron projection retraction IMP
IMP: Inferred from mutant phenotype
22649251 RGD
involved in positive regulation of ATP biosynthetic process IMP
IMP: Inferred from mutant phenotype
31172217 RGD
involved in positive regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
19336406 RGD
involved in positive regulation of axon extension IMP
IMP: Inferred from mutant phenotype
22649251 RGD
involved in positive regulation of cAMP-dependent protein kinase activity IMP
IMP: Inferred from mutant phenotype
31172217 RGD
involved in positive regulation of cardiac muscle cell apoptotic process IMP
IMP: Inferred from mutant phenotype
22106416 RGD
involved in positive regulation of cardiac muscle hypertrophy IMP
IMP: Inferred from mutant phenotype
29466442 RGD
involved in positive regulation of glycogen catabolic process IMP
IMP: Inferred from mutant phenotype
22998876 RGD
involved in positive regulation of intrinsic apoptotic signaling pathway IDA
IDA: Inferred from direct assay
23729662 RGD
involved in positive regulation of mitochondrial depolarization IMP
IMP: Inferred from mutant phenotype
31172217 RGD
involved in positive regulation of ossification IMP
IMP: Inferred from mutant phenotype
30067871 RGD
involved in positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
28386847 RGD
involved in positive regulation of peptidyl-threonine phosphorylation IMP
IMP: Inferred from mutant phenotype
22106416 RGD
involved in positive regulation of protein targeting to mitochondrion IMP
IMP: Inferred from mutant phenotype
22106416 RGD
involved in positive regulation of reactive oxygen species biosynthetic process IMP
IMP: Inferred from mutant phenotype
28386847 RGD
involved in positive regulation of vascular associated smooth muscle cell apoptotic process IDA
IDA: Inferred from direct assay
23729662 RGD
involved in regulation of membrane repolarization IMP
IMP: Inferred from mutant phenotype
32664470 RGD
involved in regulation of mitophagy IMP
IMP: Inferred from mutant phenotype
31172217 RGD
involved in spermatid development IEP
IEP: Inferred from expression pattern
14697363 RGD
Cellular Component GO Annotation Evidence Verweise Source
located in apical part of cell IDA
IDA: Inferred from direct assay
17959750 RGD
located in astrocyte end-foot IDA
IDA: Inferred from direct assay
22998876 RGD
located in axon IDA
IDA: Inferred from direct assay
16964251 RGD
located in basal part of cell IDA
IDA: Inferred from direct assay
17959750 RGD
located in central region of growth cone IDA
IDA: Inferred from direct assay
22649251 RGD
located in cytoplasm IDA
IDA: Inferred from direct assay
22649251 RGD
located in cytosol IDA
IDA: Inferred from direct assay
31754830 RGD
located in dendrite IDA
IDA: Inferred from direct assay
16964251 RGD
located in growth cone IDA
IDA: Inferred from direct assay
16964251 RGD
located in mitochondrion IDA
IDA: Inferred from direct assay
22106416 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
16964251 RGD
located in nucleus IDA
IDA: Inferred from direct assay
22649251 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adenylate cyclase type 10

  • adenylate cyclase 10 (soluble)

  • germ cell soluble adenylyl cyclase

  • soluble adenylyl cyclase

  • testicular soluble adenylyl cyclase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-132298 TDI-10229 Inhibitor 99.00% Unkown
HY-151798 TDI-11861 Inhibitor 99.35% Unkown
HY-RS00327 ADCY10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18004 Adcy10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24476 Adcy10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adcy10 NCBI NCBI:55811