hAChE-IN-1
hAChE-IN-1 (Compound 24) is a potent hAChE inhibitor with an IC50 of 1.09 μM. hAChE-IN-1 inhibits tau-oligomerization with an EC50 of 2.71 μM in cellular tau FRET assay.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C22H24N4O
- Molecular Weight:360.45
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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hAChE 1.09 μM (IC50) |
tau-oligomerization 2.71 μM (EC50) |
hAChE-IN-1 (Compound 24; 1-10 μM; 24 h) is neuroprotective in SH-SY5Y cells transfected with WT tau[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:SH-SY5Y cells transfected with WT tau
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Concentration:1, 5 and 10 μM
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Incubation Time:24 h
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Result:Improved the cell viability in a concentration-dependent manner.
Chemical Information
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Molecular Weight 360.45
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Formel C22H24N4O
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SMILES
OC(C=CC=C1)=C1C(N2CCN(CC2)C3=NC=CN=C3)C4=CC=C(C)C=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
hAChE-IN-1 Related Classifications
HY-149233 Related Classifications
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