HBV-IN-30
HBV-IN-30 (ex44), a flavone derivative, is a potent covalently closed circular DNA (cccDNA) inhibitor. cccDNA serves as the template for viral RNA transcription and subsequent viral DNA generation. HBV-IN-30 has the potential for the research of HBV infection.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 2413192-92-2
- Formel: C22H18BrClO6
- Molecular Weight:493.73
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
HBV-IN-30 (ex44; 24 h) inhibits HBeAg levels and cell viability with an IC50 value of 0.57 μM in HepDES19 cells. HepDES19 is the cell line that produces cccDNA[1].
HBV-IN-30 (5 days) decreases cccDNA levels in HepDES19 cells in a dose-dependent manner[1].
HBV-IN-30 (9 days; primary human hepatocyte (PHH)) has anti-HBV effect and inhibits HBeAg with an IC50 value of 0.04 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2413192-92-2
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Molecular Weight 493.73
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Formel C22H18BrClO6
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SMILES
ClC1=C2C(C(C=C(C3=CC(Br)=C(C=C3)OCCO[C@@H]4C[C@@H](C4)C(O)=O)O2)=O)=CC=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
HBV-IN-30 Related Classifications
HY-148781 Related Classifications
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