country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Art. -Nr.: HY-184944

Copy Link Print Information

HsClpP-ligand-1

HsClpP-ligand-1 is an intermediate derived from HsClpP ligands, and also serves as an HsClpP recruitment module for constructing mitochondria-targeted pan-PDK degraders. HsClpP-ligand-1 acts as the HsClpP ligand of the bifunctional degrader Pan-PDK degrader-1 (HY-184943).

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₂₄H₂₃N₅O₂
Molecular Weight:413.47

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

HsClpP-ligand-1 Chemical Structure

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target

HsClpP

In Vitro

HsClpP-ligand-1 (compound 16) is the HsClpP-targeting moiety of the bifunctional degrader Pan-PDK degrader-1 (compound A1) (HY-184943), and forms a stable ternary complex with recombinant human PDK1 and HsClpP^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 413.47
Formel C₂₄H₂₃N₅O₂
SMILES

OC1=C(C=CC=C1)CN2C3=NCCN3C4=C(C2=O)CN(CC4)CC5=CC=CC(C#N)=C5
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Yang Y, et al. HsClpP-Engaging Selective Mitochondrial Pan-PDK Degraders for Cancer Therapy. Journal of medicinal chemistry. 2026 Jul 02. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Angebot einholen Auf Lager

Other size

Angebot einholen