P2X7-IN-2
Based on 1 publication(s) in Google Scholar
P2X7-IN-2 (compound 58) is a P2X7 receptor inhibitor. P2X7-IN-2 inhibits IL-Iβ release with an IC50 value of 0.01 nM. P2X7-IN-2 can be used for the research of autoimmunity, inflammation and cardiovascular disease.
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- CAS. Nr.: 1058709-63-9
- Formel: C22H21F4N3O2
- Molecular Weight:435.41
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Publications Citing Use of MedChemExpress (MCE) P2X7-IN-2
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Biologische Aktivität
IC50: 0.01 nM (human whole blood IL-Iβ release)[1]
P2X7-IN-2 (0-1 μM;30 min) inhibits human whole blood IL-Iβ release with an IC50 value of 0.01 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1058709-63-9
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Molecular Weight 435.41
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Formel C22H21F4N3O2
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SMILES
O=C(NC1=C(C)C=CC2=C1C=CN([C@H](C)CN)C2=O)CC3=CC=C(C(F)(F)F)C(F)=C3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Int Immunopharmacol
CGRP alleviates epilepsy via JAK1-STAT1-P2RX7 signaling: a novel neuroprotective axis targeting neuronal damage. [Abstract]2025 Dec 21:170:116080. PMID: 41429063
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Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
P2X7-IN-2 Related Classifications
HY-18725 Related Classifications
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