PROTAC MDM2 Degrader-3
Based on 1 publication(s) in Google Scholar
PROTAC MDM2 Degrader-3 is a MDM2 self-degrading (dimeric) PROTAC. PROTAC MDM2 Degrader-3 can be used in cancer research.
(Pink: MDM2 ligand (HY-128837); Blue: MDM2 ligand (HY-128837); Black: linker (HY-W018745)).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 95.01%
- CAS. Nr.: 2249750-23-8
- Formel: C72H78Cl4N8O15
- Molecular Weight:1437.25
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) PROTAC MDM2 Degrader-3
MoreAlle PROTACs Isoform-spezifische Produkte anzeigen
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Biologische Aktivität
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MDM2 |
Chemical Information
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CAS. Nr. 2249750-23-8
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Appearance Solid
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Molecular Weight 1437.25
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Formel C72H78Cl4N8O15
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Color White to off-white
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SMILES
O=C(N1CC(N(CC(OCCOCCOCCOCCOC(CN2C(CN(C(N3[C@H](C4=CC=C(Cl)C=C4)[C@H](C5=CC=C(Cl)C=C5)N=C3C6=C(C=C(OC)C=C6)OC(C)C)=O)CC2)=O)=O)=O)CC1)=O)N7[C@H](C8=CC=C(Cl)C=C8)[C@H](C9=CC=C(Cl)C=C9)N=C7C%10=C(C=C(OC)C=C%10)OC(C)C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (1)
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Journal Impact Factor
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Most Recent
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J Cell Mol Med
2026 Apr;30(7):e71101. PMID: 41896195
Lösungsmittel & Löslichkeit
DMSO : 10 mg/mL (6.96 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6958 mL | 3.4789 mL | 6.9577 mL | 17.3943 mL |
| 5 mM | 0.1392 mL | 0.6958 mL | 1.3915 mL | 3.4789 mL |
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