RAF mutant-IN-1
RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively.
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- CAS. Nr.: 2340020-82-6
- Formel: C23H18Cl3FN6O2S
- Molecular Weight:567.85
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
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C-RAF 340D/Y341D 21 nM (IC50) |
B-RafV600E 30 nM (IC50) |
BRAFWT 392 nM (IC50) |
Chemical Information
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CAS. Nr. 2340020-82-6
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Molecular Weight 567.85
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Formel C23H18Cl3FN6O2S
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SMILES
O=C(C1=CSC2=C(N)N=CN=C21)NC3=C(C)C=CC4=C3C=CN=C4NC5=CC=C(O)C(Cl)=C5F.[H]Cl.[H]Cl
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
RAF mutant-IN-1 Related Classifications
HY-126298 Related Classifications
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