1143 Results for "

Isotype Control

" in MedChemExpress (MCE) Product Catalog:
Products (1143)

1143 Results for "Isotype Control" in MCE Product Catalog:

20
20 Publications Verification
Art. -Nr.: HY-P99001

Target:  

Inhibitory Antibodies

Forschungsgebiete:  

Inflammation/Immunology Cancer

Human IgG1 kappa, Isotype Control is a human monoclonal antibody that is the isotype control of human IgG1 kappa antibody .
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11
11 Cited Publications
Art. -Nr.: HY-P99003

Target:  

Inhibitory Antibodies

Forschungsgebiete:  

Inflammation/Immunology

Human IgG4 (S228P) kappa, Isotype Control, a human-derived monoclonal antibody, is an isotype control for human IgG4κ antibody.
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10
10 Cited Publications
Art. -Nr.: HY-P80757

Host:  

Mouse

Application:  

WB, IHC-P, IHC-F, ICC/IF, IP, FC, ChIP, ELISA, IF-Tissue, mIHC

Reactivity:  

Species independent

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8
8 Cited Publications
Art. -Nr.: HY-P99977

Target:  

Inhibitory Antibodies

Forschungsgebiete:  

Inflammation/Immunology

Mouse IgG1 kappa, Isotype Control is a negative control reagent/isotype control for mouse-derived IgG1κ antibodies. Mouse IgG1 kappa, Isotype Control, by maintaining the same immunoglobulin structure (including isotype, light chain, etc.) as the specific mouse IgG1κ subtype primary antibody, eliminates false positive signals caused by non-specific binding in immunological experiments, thus playing a core role in verifying the specificity of the experiment. Mouse IgG1 kappa, Isotype Control can be applied to immunolocalization experiments in the field of cell biology, such as immunofluorescence staining and immunohistochemistry, assisting in research on protein subcellular localization and cell structure analysis, ensuring the reliability of experimental results .
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5
5 Cited Publications
Art. -Nr.: HY-P990679

Target:  

Inhibitory Antibodies

Forschungsgebiete:  

Inflammation/Immunology Cancer

Rat IgG2a kappa, Isotype Control is a monoclonal antibody derived from rats, representing the immunoglobulin G2a (IgG2a) subclass with a kappa light chain. Rat IgG2a kappa, Isotype Control exhibits high efficiency in inducing K cell mediated cytotoxicity. Rat IgG2a kappa, Isotype Control is utilized in research investigating the roles of different immunoglobulin subclasses in tumor immunology. Rat IgG2a kappa, an isotype control, can be used as an isotype control for Anti-Mouse PD-1 Antibody (RMP1-14) (HY-P99144), Anti-Mouse CD11a/LFA-1α Antibody (M17/4) (HY-P990801), and Anti-Mouse IL-2 Antibody (S4B6-1) (HY-P990796) .
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5
5 Cited Publications
Art. -Nr.: HY-P99137

Target:  

IFNAR

Forschungsgebiete:  

Inflammation/Immunology

Anti-Mouse IFNAR1 Antibody (MAR1-5A3) is a neutralizing antibody of IFNAR1. Anti-Mouse IFNAR1 Antibody (MAR1-5A3) reacts with IFNAR1 and inhibits IFNAR1 signaling in vitro and in vivo. Mouse IgG1 kappa, Isotype Control (HY-P99977) is the isotype control of Anti-Mouse IFNAR1 Antibody (MAR1-5A3) .
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5
5 Cited Publications
Art. -Nr.: HY-P990545
CAS. Nr.: 2065212-40-8
Synonyms: ANX005

Target:  

Complement System

Forschungsgebiete:  

Neurological Disease

Tanruprubart (ANX005) is a C1q inhibitor and C1q depleter. Tanruprubart is a human antibody expressed in CHO cells, with huIgG1 heavy chains and huκ light chains, and its predicted molecular weight (MW) is 145 kDa. For the isotype control of Tanruprubart, refer to Human IgG4 kappa, Isotype Control (HY-P99003). The IC50 of Tanruprubart is 346 ng/mL for humans and 259 ng/mL for rats; its EC50 is 3.8 ng/mL for humans, 5.2 ng/mL for rats, and 9.9 ng/mL for mice. Tanruprubart is applicable to the research of Guillain-Barré syndrome and Alzheimer's disease .
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4
4 Cited Publications
Art. -Nr.: HY-P80879
Synonyms: Rabbit IgG

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, ICC/IF, IP, FC, ELISA, IF-Tissue, mIHC

Reactivity:  

Species independent

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4
4 Cited Publications
Art. -Nr.: HY-P99176

Target:  

Inhibitory Antibodies

Forschungsgebiete:  

Cancer

ATG-031 is a humanized anti-CD24 monoclonal antibody with high affinity and specificity. ATG-031 interacts with Siglec-10 expressed by tumor-associated macrophages. ATG-031 effectively stimulates macrophage-mediated phagocytosis and induces cancer cell destruction by blocking the anti-phagocytic surface proteins. ATG-031 can be used in the study of haematological malignancies as well as solid tumors. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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3
3 Cited Publications
Art. -Nr.: HY-P99979

Target:  

Fc Receptor (FcR)

Forschungsgebiete:  

Inflammation/Immunology

Rat IgG1 kappa, Isotype Control, a rat monoclonal antibody, is an isotype control for Rat IgG1κ antibody.
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2
2 Cited Publications
Art. -Nr.: HY-P99978

Target:  

Inhibitory Antibodies

Forschungsgebiete:  

Inflammation/Immunology

Mouse IgG2a kappa, Isotype Control is a negative control reagent/isotype control for mouse-derived IgG2aκ antibodies. Mouse IgG2a kappa, Isotype Control maintains the same immunoglobulin structure (including isotype, light chain, etc.) as the specific mouse IgG2aκ subtype primary antibody, thus eliminating false positive signals caused by non-specific adsorption in immunological experiments and playing a core role in verifying experimental specificity. Mouse IgG2a kappa, Isotype Control can be applied to immunolocalization experiments such as immunofluorescence staining and immunohistochemistry in the field of cell biology, assisting in protein subcellular localization, cell structure analysis, and other research to ensure the reliability of experimental results .
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2
2 Cited Publications
Art. -Nr.: HY-P99992
Human IgG1 lambda1, Isotype Control, a human-derived antibody, is an isotype control for human IgG1λ1 antibody. Human IgG1 lambda1, Isotype Control can be used in the research of diabetes and pancreatic cancer .
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2
2 Cited Publications
Art. -Nr.: HY-P991218
Synonyms: EnX203

Forschungsgebiete:  

Inflammation/Immunology

Anti-IL11 Antibody (X203) (EnX203) is a human-derived IgG1, κ type antibody inhibitor, targeting to human IL-11 . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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2
2 Cited Publications
Art. -Nr.: HY-P990587

Target:  

CD28

Forschungsgebiete:  

Inflammation/Immunology

FR104 is a humanized antibody expressed in CHO cells that targets CD28. FR104 comprises a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145.08 kDa. The isotype control for FR104 can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).
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2
2 Cited Publications
Art. -Nr.: HY-P99229
CAS. Nr.: 2254118-43-7
Synonyms: XMT-1535; Upinitatug

Target:  

ADC Antibodies

Forschungsgebiete:  

Cancer

Upifitamab is a humanized monoclonal antibody targeting NaPi2b. Upifitamab can be used to synthesize ADC such as Upfitamab rilsodotin. Upfitamab rilsodotin can be used in research for solid tumors including high-grade serious epithelial ovarian, fallopian tube and primary peritoneal cancer (OC). Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .
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2
2 Cited Publications
Art. -Nr.: HY-P990439

Target:  

IFNAR

Forschungsgebiete:  

Inflammation/Immunology

The Anti-IFNAR1 Antibody is a humanized antibody expressed in CHO cells, targeting IFNAR1. The Anti-IFNAR1 Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 144.92 kDa. The isotype control for the Anti-IFNAR1 Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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2
2 Cited Publications
Art. -Nr.: HY-P990672

Target:  

FGFR

Forschungsgebiete:  

Inflammation/Immunology

U3-1784 is a humanized antibody expressed in CHO that targets FGFR4/CD334. U3-1784 is equipped with a huIgG1 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for U3-1784 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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2
2 Cited Publications
Art. -Nr.: HY-P99100
CAS. Nr.: 2556646-63-8
Synonyms: CTL-002

Forschungsgebiete:  

Cancer

Visugromab (CTL-002) is a GDF-15 neutralizing IgG4 mAb. Visugromab has synergistic anticancer activity with the anti-PD1 antibody Nivolumab (HY-P9903) and can effectively act on PD-1/PD-L1 relapsed/refractory metastatic solid tumors. Recommend Isotype Controls: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) .
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1
1 Cited Publications
Art. -Nr.: HY-164152A
ADC Control Human IgG1-Deruxtecan (DAR 8) is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-Deruxtecan and can inhibit DNA topoisomerase I. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E) .
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1
1 Cited Publications
Art. -Nr.: HY-164152

Forschungsgebiete:  

Cancer

ADC Control Human IgG1-Deruxtecan (DAR 4) is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-Deruxtecan and can inhibit DNA topoisomerase I. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E) .
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