Sulfamerazine-d4
Based on 1 Customer Validation
Sulfamerazine-d4 is a deuterium labeled Sulfamerazine. Sulfamerazine (RP2632) is a brain-penetrant and orally active sulfonamide antibiotic and α-synuclein inhibitor with human α-synuclein KD of 352 μM. Sulfamerazine inhibits the synthesis of dihydrofolate by bacteria, thereby inhibiting bacterial growth. Sulfamerazine inhibits α-synuclein fibrillation, reduces α-synuclein aggregation-associated toxicity and α-synuclein aggregate accumulation. Sulfamerazine can be used for the research of Parkinson’s disease and bacterial infection.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.00%
- CAS. Nr.: 1020719-84-9
- Formel: C11H8D4N4O2S
- Molecular Weight:268.33
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 1020719-84-9
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Unlabeled Cas 127-79-7
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Appearance Solid
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Molecular Weight 268.33
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Formel C11H8D4N4O2S
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Color White to off-white
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SMILES
O=S(C1=C([2H])C([2H])=C(N)C([2H])=C1[2H])(NC2=NC=CC(C)=N2)=O
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Synonyms
RP2632-d4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (372.68 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7268 mL | 18.6338 mL | 37.2675 mL | 93.1689 mL |
| 5 mM | 0.7454 mL | 3.7268 mL | 7.4535 mL | 18.6338 mL | |
| 10 mM | 0.3727 mL | 1.8634 mL | 3.7268 mL | 9.3169 mL | |
| 15 mM | 0.2485 mL | 1.2423 mL | 2.4845 mL | 6.2113 mL | |
| 20 mM | 0.1863 mL | 0.9317 mL | 1.8634 mL | 4.6584 mL | |
| 25 mM | 0.1491 mL | 0.7454 mL | 1.4907 mL | 3.7268 mL | |
| 30 mM | 0.1242 mL | 0.6211 mL | 1.2423 mL | 3.1056 mL | |
| 40 mM | 0.0932 mL | 0.4658 mL | 0.9317 mL | 2.3292 mL | |
| 50 mM | 0.0745 mL | 0.3727 mL | 0.7454 mL | 1.8634 mL | |
| 60 mM | 0.0621 mL | 0.3106 mL | 0.6211 mL | 1.5528 mL | |
| 80 mM | 0.0466 mL | 0.2329 mL | 0.4658 mL | 1.1646 mL | |
| 100 mM | 0.0373 mL | 0.1863 mL | 0.3727 mL | 0.9317 mL |
Sulfamerazine-d4 Related Classifications
HY-B0512S Related Classifications
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- Sulfamerazine-d4
- 1020719-84-9
- RP2632-d4
- Isotope-Labeled Compounds
- Bacterial
- Parkinson’s disease
- meningococcal meningitis
- yeast Ure2 protein
- transgenic C. elegans
- pneumococcal infections
- gonococcal infections
- α-synuclein
- beta-hemolytic streptococcus infections
- urinary tract infections
- human neuroblastoma SH-SY5Y cells
- Inhibitor
- inhibitor
- inhibit