country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Art. -Nr.: HY-N4208

Copy Link Print Information

Taccalonolide AJ

1 Cited Publications

Kundenbewertung

Based on 1 publication(s) in Google Scholar

Taccalonolide AJ is a semi-synthesis compound with cellular microtubule stabilizing activity. Taccalonolide AJ exhibits high potency antiproliferative activity against cancer cells, with an IC₅₀ of 4.2 nM for HeLa cells.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Reinheit: 98.6%
CAS. Nr.: 2230777-09-8
Formel: C₃₄H₄₄O₁₄
Molecular Weight:676.70

Speicherung:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year

Taccalonolide AJ Chemical Structure

CAS. Nr.: 2230777-09-8

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Publications (1)
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target

microtubule^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	IC₅₀	0.0042 μM Compound: Taccalonolide AJ	Antiproliferative activity against human HeLa cells by SRB assay Antiproliferative activity against human HeLa cells by SRB assay	[PMID: 24491636]
HeLa	IC₅₀	4.2 nM Compound: 4	Antiproliferative activity against human HeLa cells by SRB assay Antiproliferative activity against human HeLa cells by SRB assay	[PMID: 24959756]
HeLa	IC₅₀	4.2 nM Compound: Taccalonolide AJ	Antiproliferative activity against human HeLa cells Antiproliferative activity against human HeLa cells	[PMID: 23855953]

Chemical Information

CAS. Nr. 2230777-09-8
Appearance Solid
Molecular Weight 676.70
Formel C₃₄H₄₄O₁₄
Color White to off-white
SMILES

C[C@]1([C@@]2(O)C)[C@]3(OC2=O)[C@H]([C@@H](C)[C@@]4([H])[C@@]1([H])[C@@H]([C@]5([H])[C@@]4([C@H]([C@@H](OC(C)=O)[C@@]6([H])[C@@]5([H])[C@H](C([C@]7([H])[C@@]6([C@H]([C@@H](O8)[C@@H]8C7)OC(C)=O)C)=O)O)OC(C)=O)C)O)O3
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

Publications (1)

All

Sort by:

Journal Impact Factor

bioRxiv

2025 Nov 12.

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 110 mg/mL (162.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

1.4778 mL

7.3888 mL

14.7776 mL

5 mM

0.2956 mL

1.4778 mL

2.9555 mL

10 mM

0.1478 mL

0.7389 mL

1.4778 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (279 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Li J, et al. Potent taccalonolides, AF and AJ, inform significant structure-activity relationships and tubulin as the binding site of these microtubule stabilizers. J Am Chem Soc. 2011 Nov 30;133(47):19064-7. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	1.4778 mL	7.3888 mL	14.7776 mL	36.9440 mL
	5 mM	0.2956 mL	1.4778 mL	2.9555 mL	7.3888 mL
	10 mM	0.1478 mL	0.7389 mL	1.4778 mL	3.6944 mL
	15 mM	0.0985 mL	0.4926 mL	0.9852 mL	2.4629 mL
	20 mM	0.0739 mL	0.3694 mL	0.7389 mL	1.8472 mL
	25 mM	0.0591 mL	0.2956 mL	0.5911 mL	1.4778 mL
	30 mM	0.0493 mL	0.2463 mL	0.4926 mL	1.2315 mL
	40 mM	0.0369 mL	0.1847 mL	0.3694 mL	0.9236 mL
	50 mM	0.0296 mL	0.1478 mL	0.2956 mL	0.7389 mL
	60 mM	0.0246 mL	0.1231 mL	0.2463 mL	0.6157 mL
	80 mM	0.0185 mL	0.0924 mL	0.1847 mL	0.4618 mL
	100 mM	0.0148 mL	0.0739 mL	0.1478 mL	0.3694 mL

Keywords

Taccalonolide AJ

1 Cited Publications

100 mg Angebot einholen

Subscribe to the

MedChemExpress

Newsletter

MOQ

Minimum order quantity

100 mg

Angebot einholen Auf Lager

Other size

Angebot einholen

Amount: USD 0.00

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Publications (1)
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise

Produktname:
Art. -Nr.:
Menge:
MCE Japan Authorized Agent:

Produktname:
CAS. Nr.:
Species:
Reinheit:
Menge:

Taccalonolide AJ

Publications Citing Use of MedChemExpress (MCE) Taccalonolide AJ

Biologische Aktivität

Chemical Information

Publications (1)

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

Taccalonolide AJ Related Classifications

HY-N4208 Related Classifications