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Cat. No.: HY-D3165

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DCM-gal-CF

DCM-gal-CF is a fluorescent probe containing a DCM fluorophore scaffold and a D-galactose recognition moiety. DCM-gal-CF itself shows weak fluorescence, and its fluorescence is enhanced after cleavage by β-galactosidase. DCM-gal-CF can be used to detect β-galactosidase activity.

For research use only. We do not sell to patients.

CAS No.: 2135433-60-0
Formula: C₃₈H₃₈N₂O₈
Molecular Weight:650.72

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

DCM-gal-CF Chemical Structure

CAS No.: 2135433-60-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

DCM-gal-CF (50 μM; 3 h) produces a 9.5-fold higher CL signal than the reference one-lock probe for detecting endogenous β-gal activity in Skov-3 cells after light irradiation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2135433-60-0
Molecular Weight 650.72
Formula C₃₈H₃₈N₂O₈
SMILES

CO/C(C1=CC(O[C@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)=CC=C1/C=C/C(OC3=CC=CC=C/43)=CC4=C(C#N)\C#N)=C5[C@@H](C6)C[C@H]7C[C@@H]6C[C@@H]\5C7
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhang Y, et al. A Sequential Dual-Lock Strategy for Photoactivatable Chemiluminescent Probes Enabling Bright Duplex Optical Imaging. Angew Chem Int Ed Engl. 2020;59(23):9059-9066. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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