LB-60-OF61
Based on 1 Customer Validation
LB-60-OF61 is a NAMPT inhibitor and is a cytotoxic compound with a selectivity towards MYC overexpressing cell lines.
For research use only. We do not sell to patients.
- Purity: 99.39%
- CAS No.: 794461-93-1
- Formula: C29H30N6O2
- Molecular Weight:494.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
NAMPT[1]
LB-60-OF61 is potent against HCT116 cells with an IC50 around 30 nM as measured in a 384 well format[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 794461-93-1
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Appearance Solid
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Molecular Weight 494.59
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Formula C29H30N6O2
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Color White to light yellow
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SMILES
O=C(C1=CC=C(OCC2=CC3=C(N=C(C#N)N=C3)N2CCC4CCCCC4)C=C1)NCC5=CC=CN=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
DMSO : 200 mg/mL (404.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0219 mL | 10.1094 mL | 20.2188 mL | 50.5469 mL |
| 5 mM | 0.4044 mL | 2.0219 mL | 4.0438 mL | 10.1094 mL | |
| 10 mM | 0.2022 mL | 1.0109 mL | 2.0219 mL | 5.0547 mL | |
| 15 mM | 0.1348 mL | 0.6740 mL | 1.3479 mL | 3.3698 mL | |
| 20 mM | 0.1011 mL | 0.5055 mL | 1.0109 mL | 2.5273 mL | |
| 25 mM | 0.0809 mL | 0.4044 mL | 0.8088 mL | 2.0219 mL | |
| 30 mM | 0.0674 mL | 0.3370 mL | 0.6740 mL | 1.6849 mL | |
| 40 mM | 0.0505 mL | 0.2527 mL | 0.5055 mL | 1.2637 mL | |
| 50 mM | 0.0404 mL | 0.2022 mL | 0.4044 mL | 1.0109 mL | |
| 60 mM | 0.0337 mL | 0.1685 mL | 0.3370 mL | 0.8424 mL | |
| 80 mM | 0.0253 mL | 0.1264 mL | 0.2527 mL | 0.6318 mL | |
| 100 mM | 0.0202 mL | 0.1011 mL | 0.2022 mL | 0.5055 mL |